This course explores a biosemiotic approach to art, our body and mind. It engages with the intrigue of meaning seeking and interpreting that has been regarded as an essential point of contact between various areas of study such as anthropology, psychology, philosophy, art history, and literary theory. To begin with, (1) the first part of the course focuses on discovering how we may become ideal interpreters by way of exerting our intuition, hypothetical thinking, and abductive reasoning. It aims to draw parallels between animals and humans in terms of sign consciousness and cognitive functions. (2) The second part empowers ideal interpreters with the skills of experiencing or reliving artistic processes so as to verify the merits of adopting the organismic approach as compared with conventional approaches in the humanities. (3) The last part draws on the concepts of agency shared by aesthetics and anthropology. It confirms the significance of unifying animal and human traits for the benefit of forming wider horizons or a mental network that serves to stage curious and numerous looks into artistic entities. All in all, this course fosters the ethics and approaches of dealing with other minds and artistic entities with a view to better surviving the world of opinions in the arts and humanities.